This add-on enables Antibiotic Sensitivity Testing (AST) for SENAITE LIMS by allowing the user to add analyses to a sample that are specifically designed for the measurement of the susceptibility of microorganisms to antibiotics. These analyses can be added either by means of pre-defined AST Panels or by direct assignment of Antibiotics and Microorganisms through a matrix.
senaite.ast also incorporates a default analysis for the identification of microorganisms present in a given sample. Once microorganisms are identified by means of this identification analysis, the system automatically populates the list of available AST Panels for selection with those that fit better with the identified microorganism(s).
Resistance analyses are qualitative and the supported results are in accordance with the new definitions of susceptibility testing categories by EUCAST 2019:
S: Susceptible, standard dosing regimen
I: Susceptible, increased exposure
Although user can configure AST Panels for the automatic addition of analyses for the capture of diameter of the zone of inhibition, the system does not automatically calculate the qualitative results based on the diameter of zone and the minimum inhibitory concentrations (MICs). However, system can infere the susceptibility testing category automatically based on pre-defined Breakpoints Tables, along with the diameter of the inhibitory zone.
Once installed, this add-on allows the laboratory to:
Maintain microorganisms (via senaite.microorganism)
Maintain antibiotics and antibiotic classes (via senaite.abx)
Maintain pre-defined AST Panels
Maintain pre-defined Breakpoints Tables
Analysis for the identification of microorganisms
Assignment of pre-defined AST Panels to a sample
Sample-level customization of AST Panel
Selective reporting of resistance results
Support for and selective reporting of extrapolated antibiotics
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